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The press have widely reported that this study shows that when a pregnancy goes beyond 42 weeks, then a child is more than two times more& 8230; Of course, these data do not exclude the possibility that other catecholamines contribute to the effect of amphetamine. Amphetamine elicits increases in synaptic norepinephrine concentrations, in addition to increasing synaptic DA. In normal animals, depletion of central norepinephrine or blockade of postsynaptic adrenergic receptors prevents the locomotor increase induced by amphetamine (Ogren et al., 1983, Archer et al., 1986, Darracq et al., 1998) suggesting a significant role for norepinephrine in the response. Further, we have found that norepinephrine contributes to the expression of locomotor hyperactivity and inattention in drug-naive coloboma mice via & x025a1; 2C -adrenergic receptors (Jones and Hess, 2003, Bruno and Hess, 2006, Bruno et al., 2007) suggesting that adrenergic receptors may also contribute to psychostimulant responses. 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The higher the dosage of Adderall administered, the greater the the dopaminergic/noradrenergic release. Auditory Processing Disorder and ADHD are two distinct clinical conditions with different diagnostic criteria. However, studies suggest that 50% of children diagnosed with ADHD may also have APD. Children with ADHD tend to exhibit inattention, distractibility, and hyperactivity in any environment, whereas children with Auditory Processing Disorder usually don have difficulty focusing and paying attention in quiet environments. Children with ADHD also usually exhibit no clear pattern on auditory processing tests and inconsistencies in APD test performance, such as ear advantage (ear strength) changes on different dichotic tests (requiring the ears to compete against each other). Although there is some overlap in symptoms, individuals with Auditory Processing Disorder present primarily with complaints of poor listening skills and frequent requests for clarification, while individuals with ADHD present primarily with complaints of inattentiveness and/or hyperactivity. Children with ADHD have been shown to be more accident prone than other children , likely because of their tendencies toward impulsive, overactive behavior. They are also more likely than other children to experience injuries due to accidents, such as broken bones, lacerations, head injuries, bruises, lost teeth, or accidental poisonings [54,55]. One study has estimated the incidence and cost of accidents among individuals with ADHD using an administrative database of medical, pharmaceutical, and disability claims for national manufacturers' employees, spouses, dependents, and retirees . Analyses were conducted for the whole population, adults alone, children under age 12, and adolescents aged 12 to 18 years. ADHD patients in all age groups were more likely than a matched control group to have at least one accident claim: children, 28% versus 18%; adolescents, 32% versus 23%, and adults, 38% versus 18%. Among adults, the accident-specific direct medical. 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